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Introduction:
NEVELIA® bi-layer matrix is a sterile medical device consisting of a collagen layer to promote dermal regeneration and a reinforced silicone layer acting as a pseudo-epidermis.

Properties:
The type I, purified, stabilized, bovine origin collagen is supplied as a porous matrix. This matrix serves as a support for cell infiltration, thus contributes to the natural tissue regeneration process. It is resorbed; becoming a vascularized tissue that is histologically very close to the normal dermis, from 2 to 3 weeks after it is implanted. The silicone layer consists of medical-grade silicone elastomer reinforced with a polyester material. It acts as a "pseudo-epidermis", protecting the wound from bacterial infection and other damage. It is removed after dermal regeneration, at the time of the thin split thickness skin graft. This dermal substrate promotes regeneration of normally functioning and aesthetically satisfactory skin.

Indications:
NEVELIA® Bi-Layer Matrix is indicated for dermal regeneration in individuals with skin loss, particularly in the following fields:
• Burns surgery (third and deep second degree burns)
• Reconstructive plastic surgery
• Traumatology
NEVELIA® Bi-Layer Matrix is used in combination with a thin split thickness skin graft (STSG) to recreate skin resembling normal skin in terms of function and appearance.

NEVELIA® Bi-Layer Matrix is particularly useful for:
• Patients who are unable to supply sufficient donor skin for an autograft at the time of excision
• When the physiological condition of the patient does not allow the autograft

Method of administration:
All the dead tissue on and around the area receiving the graft must be carefully removed, leaving only viable tissue. For NEVELIA®bi-layer matrix to take successfully and to prevent infection, all necrotic and scar tissues must be excised.
It is important to make sure that haemostasis is complete before applying NEVELIA®bi-layer matrix, to prevent the development of hematomas which may cause local failure of NEVELIA®bi-layer matrix to take.
The matrix can be meshed if used for highly exudative wounds or to improve the fit of the bi-layer matrix to an irregular surface. NEVELIA®bi-layer matrix must not be expanded.
NEVELIA® bi-layer matrix must be applied on the day the necrotic or dead tissue is excised or when a viable, vascularised wound bed has been obtained. Delayed application after excision may jeopardize integration of the matrix into the wound bed.

NEVELIA®bi-layer matrix must be cut to fit the excised wound exactly. This will minimize scarring. It is important to ensure that the matrix is inserted into the wound with the collagen layer directly against the viable wound bed, and the silicone layer facing outwards

Presentation and size:
This dermal regeneration template is presented in 4 sizes
• Ref MCS0505 : 5 cm x 5 cm
• Ref MCS1015 : 10 cm x 15 cm
• Ref MCS1030 : 10 cm x 30 cm
• Ref MCS2030 : 20 cm x 30 cm

NEVELIA bi-layer matrix is supplied -hydrated between two protective sheets of plastic in double pouches. Each pack contains one bi-layer matrix and is radiation-sterilized.Look how we write essay writing essays here - buy essay, welcome. Also we write essay writer essays here.
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